Anticancer Action and Pharmacokinetics of Sesquiterpene Lactone Extracts of Yacon Leaves

Purification and identification of antimicrobial sesquiterpene lactones from yacon (Smallanthus sonchifolius) leaves.

The extraction of yacon [Smallanthus sonchifolius (Poepp. and Endl.) H. Robinson; Asteraceae] leaves and chromatographic separation yielded two new antibacterial melampolide-type sesquiterpene lactones, 8beta-tigloyloxymelampolid-14-oic acid methyl ester and 8beta-methacryloyloxymelampolid-14-oic acid methyl ester, as well as the four known melampolides, sonchifolin, uvedalin, enhydrin and fluc...

The Antiinflammatory Sesquiterpene Lactone

Topical anti - inflammatory activity of yacon leaf extracts

Smallanthus sonchifolius (Poepp.) H. Rob., Asteraceae, known as yacon, is an herb that is traditionally used for the treatment of diabetes in folk medicine. However, recent studies have demonstrated that this plant has other interesting properties such as anti-microbial and anti-infl ammatory actions. Thus, the purpose of this study was to evaluate the topical anti-infl ammatory property of dif...

Article 14.indd

Smallanthus sonchifolius (Poepp.) H. Rob., Asteraceae, known as yacon, is an herb that is traditionally used for the treatment of diabetes in folk medicine. However, recent studies have demonstrated that this plant has other interesting properties such as anti-microbial and anti-infl ammatory actions. Thus, the purpose of this study was to evaluate the topical anti-infl ammatory property of dif...

Effect of crude extracts of leaves of Smallanthus sonchifolius (yacon) on glycemia in diabetic rats

The present study investigated the effect of crude extracts from yacon leaves, obtained by aqueous cold (YC) or hot (YH) extraction, or hydroethanolic extraction (YE), on glycemia of the diabetic (induced by streptozotocine, 50 mg/kg, ip) and nondiabetic rats. The animals were treated orally with the extracts (400 mg/kg) or water for 3, 7, 10, and 14 days. After this period, the animals were an...